{"id":1102,"date":"2026-02-13T20:17:30","date_gmt":"2026-02-13T19:17:30","guid":{"rendered":"https:\/\/bezugla.de\/mounjaro-tirzepatid-durchbruch-oder-ueberschaetztes-wundermittel\/"},"modified":"2026-10-27T16:14:39","modified_gmt":"2026-10-27T15:14:39","slug":"mounjaro-tirzepatide-breakthrough-or-overhyped","status":"publish","type":"post","link":"https:\/\/bezugla.de\/en\/mounjaro-tirzepatide-breakthrough-or-overhyped\/","title":{"rendered":"Mounjaro (Tirzepatide) \u2013 Breakthrough or Overhyped Wonder Drug?"},"content":{"rendered":"\n<aside class=\"reviewed-by-block\" style=\"border-left:3px solid #2f6e6e;padding:10px 14px;margin:0 0 1.5em 0;background:#f3f7f7;font-size:0.92em;line-height:1.5\">\n<p style=\"margin:0;font-weight:600\">Content reviewed by <a href=\"https:\/\/bezugla.de\/en\/about-us\/\">Olha Bezuhla<\/a><\/p>\n<p style=\"margin:3px 0 0 0;color:#555\">Nutritional consultant \u00b7 Center for Prevention and Nutrition, Berlin<\/p>\n<\/aside>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-bbc1d55c wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1536\" height=\"1024\" src=\"https:\/\/bezugla.de\/wp-content\/uploads\/2026\/02\/mounjaro.png\" alt=\"\" class=\"wp-image-704\" srcset=\"https:\/\/bezugla.de\/wp-content\/uploads\/2026\/02\/mounjaro.png 1536w, https:\/\/bezugla.de\/wp-content\/uploads\/2026\/02\/mounjaro-900x600.png 900w, https:\/\/bezugla.de\/wp-content\/uploads\/2026\/02\/mounjaro-720x480.png 720w, https:\/\/bezugla.de\/wp-content\/uploads\/2026\/02\/mounjaro-600x400.png 600w\" sizes=\"(max-width: 1536px) 100vw, 1536px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"wp-block-paragraph\">In recent years, so-called incretin-based injections have received considerable media attention. The name <strong>Mounjaro\u00ae (active substance: tirzepatide)<\/strong> is mentioned particularly often.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In public discussion, this often creates the impression of a \u201cmiracle drug\u201d.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the Center for Prevention and Nutrition in Berlin-Moabit, we view such developments in a differentiated way and on the basis of scientific evidence.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>What is Mounjaro (tirzepatide)?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tirzepatide is an injectable active substance that was originally developed in a medical professional context for people with type 2 diabetes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It belongs to the group of dual GIP and GLP-1 receptor agonists and is prescribed and monitored by a physician.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2022 Classified as a dual GIP and GLP-1 receptor agonist<br>\u2022 Use only after medical prescription<br>\u2022 Medical follow-up monitoring<br>\u2022 Possible undesirable accompanying effects<\/p>\n<\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Tirzepatide is now being studied and used in certain medical indications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>What is known from clinical investigations?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The clinical studies of the SURPASS and SURMOUNT programs investigate tirzepatide compared with placebo in defined patient groups.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The SURMOUNT-1 study investigated different dosages over 72 weeks in adults according to specified inclusion criteria (Jastreboff et al., 2022).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038\">Study publication<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2107519\">Further study publication on tirzepatide in a medical context (Frias et al., 2021)<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The publications describe tirzepatide as a prescription-only active substance whose use must be assessed medically.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Is it a \u201cmiracle drug\u201d?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Media coverage often suggests a simple solution to complex metabolic problems.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">From a professional perspective, tirzepatide is a prescription-only active substance \u2013 but not a substitute for comprehensive support.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Several aspects need to be considered:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2022 Discontinuing therapy may be associated with weight gain<br>\u2022 Long-term data over several years are limited<br>\u2022 Side effects such as gastrointestinal complaints are common<br>\u2022 Drug therapy does not replace structural lifestyle change<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When body weight is significantly elevated, several factors often interact. Medically prescribed medicines can be incorporated into an overall concept, but they do not replace a sustainable strategy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Body composition instead of weight alone<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A key point in the discussion:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Weight reduction does not automatically mean optimal body composition.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When body weight changes, muscle mass as well as fat mass must be taken into account. Maintaining muscle mass is, however, central to metabolic stability.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For accompanying micronutrient supply, for example, <a href=\"https:\/\/bezugla.de\/en\/product\/biogena-omega-3-forte-700\/\">Omega 3 forte 700<\/a> may be considered: It provides 700 mg EPA and DHA per capsule; EPA and DHA contribute to the normal function of the heart. The beneficial effect is obtained with a daily intake of 250 mg EPA and DHA. Food supplements are not a substitute for a balanced, varied diet and a healthy lifestyle. The stated recommended daily intake must not be exceeded.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the Center for Prevention and Nutrition in Berlin-Moabit, the focus is therefore not solely on body weight, but on the differentiated analysis of body composition over time.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>When can a medical assessment be important?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A medical assessment can be important in certain situations, particularly:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2022 In cases of significantly increased body weight and additional health factors<br>\u2022 When previous nutrition and exercise measures are not sufficient<br>\u2022 As part of structured medical care<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The decision is made individually and on medical grounds.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Center for Prevention and Nutrition does not prescribe medicines, but offers structured preventive support as a supplement to medical care.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Conclusion<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mounjaro (tirzepatide) is not a \u201cmiracle drug\u201d, but a prescription-only medicinal product whose use must be assessed by a physician.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Long-term metabolic stability, however, requires:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2022 Structured support<br>\u2022 Follow-up monitoring<br>\u2022 Differentiated consideration of body composition<br>\u2022 Sustainable adjustment of lifestyle factors<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Medicines can be part of an overall medical concept \u2013 but they do not replace a structured prevention strategy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As a complementary herbal formulation during structured lifestyle adjustments, <a href=\"https:\/\/bezugla.de\/en\/product\/biogena-ashwagandha-fusion-complete-120-capsules\/\">Ashwagandha Fusion Complete<\/a> may be considered: It combines KSM-66\u00ae ashwagandha root extract with other selected plant extracts.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Interested in structured support?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the Center for Prevention and Nutrition in Berlin-Moabit, preventive support is based on a differentiated body analysis and documented monitoring over time.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You can find further information in the areas<br><strong>\u201cBody Analysis\u201d and \u201cPrevention Programs\u201d of the Center for Prevention and Nutrition.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Literature<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038\">Jastreboff, A.M. et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. <em>New England Journal of Medicine.<\/em><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2107519\">Frias, J.P. et al. (2021). Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. <em>New England Journal of Medicine.<\/em><\/a><\/p>\n\n\n\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n<div class=\"article-author-bio\" style=\"margin-top:2em;padding-top:1.2em;border-top:1px solid #e0e0e0\"><p><strong>Author of the article:<\/strong> <a href=\"https:\/\/bezugla.de\/en\/about-us\/\">Olha Bezuhla<\/a> \u2014 Nutritional consultant with a medical background: studies in human medicine (Pirogov National Medical University), specialization in nutritional science. Doctorate in social medicine, postdoctoral scientist at the German Institute of Human Nutrition (DIfE), Potsdam-Rehbr\u00fccke. <a href=\"https:\/\/bezugla.de\/en\/about-us\/\">More about the author<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>Content reviewed by Olha Bezuhla Nutritional consultant \u00b7 Center for Prevention and Nutrition, Berlin In recent years, so-called incretin-based injections have received considerable media attention. The name Mounjaro\u00ae (active substance: tirzepatide) is mentioned particularly often. In public discussion, this often creates the impression of a \u201cmiracle drug\u201d. At the Center for Prevention and Nutrition in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1101,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[34],"tags":[],"class_list":["post-1102","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"wpml_lang":"en","wpml_translations":{"trid":"67","translations":{"de":"506","en":"1102","uk":"2692","ru":"2759"}},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mounjaro (Tirzepatide): Effects, Risks &amp; Assessment | bezugla.de<\/title>\n<meta name=\"description\" content=\"What is Mounjaro? Effects, side effects and scientific classification for weight reduction and metabolic regulation. 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